| Claypole Branch | rises in S Transylvania County and flows NE into Middle Fork French Broad River. |
| Clayroot | community in SE Pitt County. |
| Clayroot Swamp | rises in SE Pitt County and flows SW and SE into Swift Creek. For a part of its course, it forms the boundary between Craven and Pitt Counties. |
| Clayton | town in NW Johnston County. Inc. 1869. Known previously as Stallings Station. Named for a local school, Clayton Academy, or for Senator John M. Clayton (1796-1856) of Delaware, coauthor of the Clayton-Bulwer Treaty of 1850 with Great Britain. Alt. 345. Produces textiles and apparel. |
| Clayton Bay | swamp NW Brunswick County. A part of Green Swamp. |
| Clayton Branch | rises in SE Cherokee County and flows NW into Little Brasstown Creek. |
| Clayton Creek | rises in S Buncombe County and flows NE into French Broad River. |
| Clayton Hall | See Rocky Point. |
| Clayton Township | NW Johnston County. |
| Clear Branch | rises in E Watauga County and flows SE into Elk Creek. |