| Esmeralda | community in NW Rutherford County on Broad River. |
| Ess-ee-daw | See Broad River. |
| Essex | town in SW Halifax County. Inc. 1891, but long inactive in municipal affairs. Prior to 1860 it was the center of a settlement of free blacks. |
| Essex Island | See Etacrewac. |
| Estatoe | community in S Mitchell County on Brushy Creek. Named for the daughter of an Indian chief. |
| Estatoe | See Rosman. |
| Estatoe Path | S Transylvania County, trading route between settlements of Cherokee Indians and their town of Estatoe, now in South Carolina. |
| Estatoe River | See Toe River. |
| Estelle | community in NE Caswell County. A post office operated there during the approx. period 1880-1905. |
| Estes Branch | rises in N Swain County and flows SW into Indian Creek. |