| Orton Branch | rises in S Buncombe County and flows NE into French Broad River. |
| Orton Creek | rises in SE Brunswick County and flows E into Cape Fear River. |
| Orton Plantation | E central Brunswick County overlooking Cape Fear River. House, built about 1725 by Roger Moore and later the home of Governor Benjamin Smith, is now a tourist attraction with extensive azalea gardens. The old town of Brunswick, which see, was nearby. |
| Orton Point | point of land S of mouth of Lilliput Creek in E Brunswick County extending into Cape Fear River. |
| Orton Pond | artificial pond on Orton Creek in E Brunswick County. Built about 1810. Max. depth 12 ft. Surface area 500 acres. |
| Os-quee-ha-ha | See Clear Creek. |
| Osage Mountain | S Macon County between West Fork Overflow Creek and Watkins Creek. |
| Osborn Branch | rises in NE Transylvania County and flows SE into Boylston Creek. |
| Osborn Mountain | E Watauga County between Elk Creek and Southwest Stony Fork Creek. |
| Osborne | community in S Richmond County. |