| Orion | community in SE Ashe County. |
| Orlando | community in S Macon County. |
| Orleans | community in SW Lincoln County served by post office, 1886-1906. |
| Ormonds Township | SE Greene County. Named for the Ormond family, which settled in the Ormondsville community prior to 1769. |
| Ormondsville | community in E Greene County. Developed from a country crossroads store at the Ormond family plantation. |
| Orris's Run | swampy stream rises in N central Beaufort County and flows SE into Pungo Creek. Named for Orris Waters who lived nearby. |
| Orrum | town in S Robeson County. Settled as early as 1832 as a community around Big Branch Church. Inc. 1903. Orton was the first choice for a name in 1903 when a post office was about to be est., but as the name was already in use in Columbus County, it was rejected. Orrum was coined as a variant of Orton. |
| Orrum Township | SE Robeson County. |
| Orton | community in E central Brunswick County on Cape Fear River. |
| Orton | community in N Columbus County served by post office, 1883-1904. |