23 June 1733–Apr. 1784

On 14 Sept. 1768 a commission was issued naming him lieutenant governor of North Carolina. In July 1769 Henry Eustace McCulloh, then in London, wrote to John Harvey that "Col. Mercer of Virginia has been for sometime appointed your Lieut Govr & I do believe has thoughts of succeeding: when Mr Tryon leaves America." This did not materialize, however, but Mercer was named a member of the North Carolina Council in 1771 in the commission of Governor Josiah Martin, who was Tryon's successor. There is no clear evidence that Mercer ever was in the colony, although the Virginia Gazette of 23 Mar. 1769 reported that "the Honorable George Mercer, Esq; Lieutenant Governor of North-Carolina is arrived at Newbern in that province." Mercer, as a matter of fact, was in London for long periods representing the Ohio Company. In November 1771 Martin referred to a report that Mercer was about to become governor of a new colony on the Ohio, but again this never occurred.
A Loyalist in sympathy, Mercer went to England sometime before the American Revolution. There a series of misfortunes and disappointments culminated in his physical impairment and insanity. He was in France for his health in 1777, when he was informed that his commission as lieutenant governor of North Carolina was still in effect. In 1783 his wife asked the Lords Commissioners of the Treasury to continue his allowance and sought reimbursement for losses he had sustained as stamp distributor. He died in England.