| Mayo Mountain | on W side of Mayodan, extends 2 mi. from Beaver Island Creek toward Dan River. Rises about 300 ft. |
| Mayo River | rises in Patrick County, Va., and flows SE into Rockingham County and into Dan River. Named for William Mayo, member of William Byrd's surveying party, 1728. |
| Mayo River State Park | in NW Rockingham County. Est. in 2003 with plans for hiking trails and canoe access. |
| Mayo Township | NW Rockingham County. |
| Mayodan | town in W Rockingham County on Mayo River. Built as textile mill village. Inc. 1899. Named for nearby Mayo River and Dan River. Alt. 594. See also Avalon. |
| Mayonia | See Whitakers. |
| Mayos Crossroads | community in SE Edgecombe County. |
| Mays Crossroads | community in W Franklin County. |
| Maysville | town in S Jones County on White Oak River. Inc. 1897. A post office est. there in 1827 was known as Cross Roads. It appears to be the "Young's Cross Roads" that is mentioned frequently in Civil War official records. Alt. 41. |
| Mayview Hill | S Watauga County on the head of China Branch. |