| Little Shocco Creek | rises in SW Warren County and flows E into Shocco Creek. |
| Little Shuckstack | mountain in Great Smoky Mountains National Park, NW Swain County, lat. 35°29'26" N., long. 83°48'37" W. Alt. 3,821. |
| Little Silver Creek | rises in SW Burke County and flows NE into Silver Creek. |
| Little Singletary Lake | a natural lake in N Bladen County; approx. 1½ mi. long and ¾ mi. wide. Fishing. See also Carolina Bays. |
| Little Snow Creek | rises in N Stokes County and flows SE into Snow Creek. |
| Little Snowball Mountain | N Buncombe County between Cherry Log Gap and Snowball Gap. Alt. 4,824. |
| Little Snowbird Creek | rises in S Graham County and flows NE and NW into Snowbird Creek. |
| Little Spivey Creek | rises in N Yancey County and flows W into Tennessee, where it enters Spivey Creek. |
| Little Spruce Ridge | W Haywood County in Great Smoky Mountains National Park, a spur extending NE from Cataloochee Divide; center near lat. 35°33'35" N., long. 83°08'04" W., between Little Bald Branch and Bearpen Branch. |
| Little Steeltrap Creek | rises in N Swain County and flows SW into Forney Creek. |