| South Williams Township | S Columbus County. |
| South Wilmington | unincorporated outskirts of the city of Wilmington, W New Hanover County on the Cape Fear River. |
| South Yadkin River | rises in NE Alexander County and flows SE across Iredell County and to the Davie-Rowan county line, which it forms to its junction with Yadkin River. Also sometimes known as South Fork Yadkin River. Appears as "Sapona or Yatkin River" on the Moseley map, 1733. See also Cedar Run Creek; Mill Fork. |
| Southeast Muddy Creek | rises in SE McDowell County and flows NE into South Muddy Creek. |
| Southerlands Millpond | in E Vance County on Sandy Creek. Area 30 acres; max. depth 10 ft. Now used by the city of Henderson as a reservoir. See also Millford. |
| Southern City | See East Spencer. |
| Southern Mountain | central Transylvania County between Brushy Creek and Burl Mountain. |
| Southern Pines | town in S Moore County. Inc. 1887. Known earlier as Vineland, but the Post Office Department would not accept the name because of possible confusion with the town of the same name in New Jersey. Named for its location on the edge of the longleafpine belt. A popular winter resort. West Southern Pines, inc. 1923, became a part of Southern Pines in 1931. Alt. 516. Sandhills Community College, est. 1965, is located there. |
| Southern Plantation | See South Virginia. |
| Southern Shores | town and resort community in NE Dare County on the S coast of North Banks between Kitty Hawk and Duck. Inc. 1969. |