| Schoolhouse Branch | rises in NE Cherokee County and flows SE into Junaluska Creek. |
| Schoolhouse Branch | rises in S Haywood County and flows SW into Little East Fork Pigeon River. |
| Schoolhouse Branch | rises in central Pitt County and flows NE into Tar River. |
| Schoolhouse Flats | E Haywood County on Glade Mountain. |
| Schoolpath Branch | rises in S central Transylvania County and flows NE into West Fork French Broad River. |
| Schooner Creek | rises in SE Beaufort County and flows N into South Creek. |
| Schooners Bay | See Spooners Bay. |
| Schuler Cove | See Jack Cove. |
| Schulkens Pond | a natural lake in SE Columbus County approx. 7 mi. SW of Lake Waccamaw and 1 mi. W of Waccamaw River. Bear Branch drains Schulkens Pond into Waccamaw River. |
| Science | community in SW Randolph County. |