| Notla Township | S central Cherokee County. |
| Nottely River | rises in Georgia and flows N into Cherokee County, through which it flows n, w, and NE into Hiwassee River about 2 mi. W of Murphy. |
| Nottoway River | rises in Virginia and flows SE into Hertford County, where it joins Blackwater River on the Gates-Hertford county line to form Chowan River. Nottoway, meaning "adders" or "rattlesnakes," was a name applied by Algonquian neighbors to Indians in the area. The name Nataway River appears on the Ogilby map, 1671, intended for the river but mistakenly applied to the present Wiccacon River. See also Weyanoke Creek. |
| Notts Island | See Mackay Island. |
| Nova Scotia Branch | rises in SW Macon County and flows NW into Nantahala River. |
| Nubbin Ridge | See Jones Chapel. |
| Nubbinscuffle Creek | rises in W Yancey County and flows S into Bald Creek. |
| Nuna Ridge | NW Swain County in Great Smoky Mountains National Park between Tub-Mill Creek and Gunna Creek. |
| Nunda Branch | in Great Smoky Mountains National Park, rises in NW Swain County and flows SE into Bone Valley Creek. |
| Nunn Mountain | SE Orange County on the head of Booker Creek. |