| Skiffly Branch | rises in W Madison County and flows S into Roaring Fork. |
| Skin Cabin Creek | rises in S Surry County and flows SE into Ararat River. |
| Skinner Canal | N Washington County, drains N from East Dismal Swamp to Kendricks Creek. Known in 1868 as McRae Canal. |
| Skinner's Point | See Hornblower Point. |
| Skinnersville | community in N Washington County. Post office est. in 1808 with service until 1908. Name was changed to Leo. The site of the community having moved to the ne, the old site became known locally as Old Skinnersville. |
| Skinnersville Township | NE Washington County, was formed in 1868. |
| Skipper Branch | rises in S central Brunswick County and flows S into Shallotte Creek. |
| Skitty Creek | rises in E Macon County and flows S into Cullasaja River. |
| Skull Camp Mountain | NW Surry County. Alt. 2,082. A post office, Scull Camp, served the area, 1800-1856. The name appears on the U.S. Coast Survey map, 1865. |
| Skunk Creek | rises in central Lee County and flows NW into Big Buffalo Creek. |