| South Fayetteville | unincorporated outskirts of city of Fayetteville in central Cumberland County. |
| South Flat River | rises in SW Person County and flows SE into Flat River. |
| South Fork | rises in S Forsyth County and flows SW into Davidson County, where it enters Muddy Creek a short distance S of the county line. Early Moravian settlers called it Ens Creek, and it appears as such on the Collet map, 1770. On the Price map, 1808, it is marked "Ens or South Fork." |
| South Fork | rises in S Henderson County and flows NW into Willow Creek. Also known locally as Greer Creek. |
| South Fork | rises in N McDowell County near Betsy and Hensley Ridges and flows SE into Toms Creek. |
| South Fork | rises in NW McDowell County on the N slope of Pups Ridge and flows SE into Roses Creek. |
| South Fork | rises in W Surry County and flows SE into Mitchell River. |
| South Fork | rises in E Transylvania County and flows SE into W Henderson County, where it flows NE to join North Fork in forming Mills River. Sometimes also known as South Fork Mills River. |
| South Fork | See South Fork Catawba River. |
| South Fork Beech Creek | rises in E Graham County and flows NW into Beech Creek. |