| Sodom Hollow | central Buncombe County, the valley through which French Broad River flows NW of Asheville toward Dryman Mountain. Named by an early circuit rider, who compared the rough pioneers living there with the inhabitants of the biblical Sodom and Gomorrah. |
| Sodom Mountain | central Madison County between Walnut Gap and Lumptown. |
| Soggy Hill Branch | rises in NE Swain County and flows S into Raven Fork. |
| Sokassa | See Rumbling Bald Mountain. |
| Solitude | See Ashland. |
| Solola Valley | community in N central Swain County on Noland Creek. The name comes from salola, the Cherokee Indian word for squirrel. |
| Solomons Creek | rises in S Richmond County and flows W into Pee Dee River. |
| Solray Gap | central Haywood County between Little Pine Mountain and Pigeon River. |
| Sols Creek | rises in E Jackson County and flows SW into Bear Creek Lake on the Tuckasegee River. |
| Somers Township | SE Wilkes County. |