| Medlock Mountain | See Meadlock Mountain. |
| Medoc | community in W Halifax County between Brinkleyville and Ringwood. Named for nearby Medoc Mountain. |
| Medoc Mountain | a comparatively high hill on the E bank of Little Fishing Creek, W Halifax County; center of a state park. Named for a vineyard est. there in the late nineteenth century and named for Médoc, France, which contains some of that country's most famous vineyards. "Rocky Hill," the summer home of Governor Hutchins G. Burton (1774-1832), was nearby. |
| Medora | community in W Edgecombe County. |
| Meege Crossroads | community in N Chowan County. A post office operated there, 1902-25, called Meege, which was the nickname of Mrs. Miles Elliott, wife of the postmaster. |
| Meeksville | community in W Wilson County served by post office, 1878-1901. |
| Meeting House Branch | rises in E central Wilson County and flows SW in an arc into Buck Branch. Name appears in local records as early as 1775. |
| Meeting of the Waters | creek in SE Orange County rising just S of the town of Chapel Hill and flowing SE into Morgan Creek. |
| Meetinghouse Branch | rises in N central Sampson County and flows SE into Great Coharie Creek. |
| Meetinghouse Mountain | extends NE from Stecoah Creek to Little Tennessee River in NE Graham County. |