| Chambers Creek | rises in W Cherokee County and flows SW into Hiwassee Lake. |
| Chambers Creek | rises in N Swain County and flows SW into Fontana Lake. |
| Chambers Creek Gap | N Swain County on Welch Ridge near the head of Bear Creek. Named for John Chambers, an early settler. |
| Chambers Mountain | E Haywood County, extends NE from the head of Long Branch to the head of Rogers Cove Creek. |
| Chambersburg Township | SE Iredell County. Named for local Chambers family. |
| Champion | community in SW Wilkes County near South Prong Lewis Fork Creek. |
| Chancandepeco Inlet | from the Atlantic Ocean into Pamlico Sound through Hatteras Island N of Cape Hatteras, SE Dare County. Opened prior to 1585 and closed prior to 1657. Appears as Chacandepeco on the Velasco map, 1611. The name is possibly a Spanish spelling for an Algonquian Indian word meaning "it dips and disappears as shallows." |
| Chance | community in W Sampson County served by post office, 1889-1904. |
| Chandler | community in NE Montgomery County served by post office, 1875-1927. Known as Chandler's Grove until 1894. |
| Chandler Creek | rises in E Madison County and flows SE into California Creek. |