| Conway Creek | See Little Fishing Creek. |
| Conwell | community in SE Northampton County on the E limits of Rich Square. |
| Coohooca | See Cohoogue. |
| Cook | community in SW Catawba County served by post office, 1895-1905. |
| Cook Branch | rises in S Watauga County and flows NE into Pounding Mill Creek. |
| Cook Branch | rises in N Mitchell County and flows S into Little Rock Creek. |
| Cook Branch | rises in E Graham County and flows NE into Rock Creek. |
| Cook Branch | rises in N Madison County and flows S into Big Laurel Creek. |
| Cook Creek | rises in N Cherokee County and flows SW into Garreck Creek. |
| Cook Creek | See Island Creek. |