| Striking Island | a tidal-marsh island in the Cape Fear River opposite Southport, SE Brunswick County. |
| Stringfellow Branch | rises in S Watauga County in Moses H. Cone Memorial Park and flows E through Bass Lake and into Chetola Lake on Middle Fork [South Fork New River]. |
| Strouds Creek | rises in N Orange County and flows SE into Eno River. |
| Strouph Gap | on the SW end of Burney Mountain on the Buncombe-Henderson county line. |
| Stuards Reach | appears on the Smith map, 1624, in what is now the Roanoke River between Halifax and Northampton Counties. |
| Stuart Creek | rises in NW Henderson County in Pisgah National Forest and flows NE into North Fork. |
| Stubblefield | community in NW Caswell County. Named for a local family. |
| Stubblefield | See Ruffin. |
| Stubbs | community in E Cleveland County on Buffalo Creek. Alt. 950. Settled about 1885. Named for Col. Seth W. Stubbs, who made the clock for the Lincoln County Courthouse, 1856. |
| Stump Inlet | or former inlet from the Atlantic Ocean to Stump Sound, SE Onslow County. Appears on the Moseley map, 1733, and on other maps through 1882. Apparently closed by 1912. |