| Little Creek | rises in N Stokes County and flows SW into Peters Creek. |
| Little Creek | rises in W Surry County and flows SE into Snow Creek. |
| Little Creek | rises in E Wake County and flows SE into N Johnston County, where it enters Moccasin Creek. |
| Little Creek | rises in N Yancey County and flows SE into Cane River. |
| Little Creek | community on Little Creek S of Sams Gap, NE Madison County. Alt. 2,892. |
| Little Creek Gap | on the Haywood-Madison county line. |
| Little Creek Point | S Onslow County in New River. |
| Little Crooked Creek | rises in SW McDowell County and flows E into Crooked Creek. |
| Little Cross Creek | rises in N Cumberland County and flows SE into Cross Creek. Early settlers found that Cross Creek and Little Cross Creek crossed. |
| Little Cub Creek | See East Prong Cub Creek. |