| East Sanford Township | former township in central Lee County. Now township no. 5. |
| East Spencer | town in E Rowan County. Originated as Southern City (along the route of the Southern Railway), a real-estate development by John S. Henderson and others. Inc. 1901. The town of Spencer is to the sw. "Spring Hill," plantation of Maxwell Chambers, was there. |
| East Swan Creek | rises in W Yadkin County and flows NW into Wilkes County, where it joins West Swan Creek in forming Swan Creek. |
| East Wilmington | unincorporated outskirts of the city of Wilmington, W New Hanover County. |
| East Woodford | community in SE Mecklenburg County. |
| Eastatoe Creek | rises in NE Pickens County, S.C., in the Blue Ridge Mountains and flows N into S Transylvania County, N.C., and NE into Middle Fork French Broad River. |
| Eastatoe Gap | S Transylvania County between Shoal Creek and Eastatoe Creek. Alt. 2,686. |
| Eastatoe Township | S central Transylvania County. |
| Eastbrook | community in NE Brunswick County. |
| Eastern Channel | a tidal waterway in SW Brunswick County extending E from Tibbs Inlet inside Hales Beach for about 3 mi. |