| Straight Fork | rises in NE Swain County in Great Smoky Mountain National Park and flows S and SW into Raven Fork. |
| Straits | community in SE Carteret County on a point of land extending into the mouth of North River. |
| Straits Township | on The Straits in central Carteret County. At one time, a portion of Straits was called no. 5 township. From Straits were formed Carteret and no. 9 townships (both now abolished) and Merrimon. |
| Straits, The | straits in the waters between North River and Core Sound in SE Carteret County between Harkers Island and the mainland. |
| Strange Branch | rises in NE Cherokee County and flows SE into Big Cove Branch. |
| Strangenbergs Creek | See Silas Creek. |
| Stratford | community in W central Alleghany County. |
| Stratton Bald | W Graham County at NW end of Horse Cove Ridge. Alt. approx. 5,380. |
| Stratton Branch | rises in NW Swain County and flows SE into Lake Cheoah. |
| Straw | community in S Wilkes County near East Prong Cub Creek. |