| Slocomb | community in N Cumberland County. |
| Slocomb Crossroads | See Turlington. |
| Slocum Creek | rises in SE Craven County and flows N into Neuse River. Appears on the Moseley map, 1733, as Slocumbs Creek. |
| Sloop Point | extends from the mainland of S Pender County into Virginia Creek estuary in Topsail Sound. Named for the fact that sloops entering the sound moored there. Sloop Point post office, 1879-1936, was located at what is now Barlowes, which see. Site of oldest house in North Carolina, "Sloop Point" (ca. 1726). |
| Slosh | See Schlosstown. |
| Slough, The | stream, rises in N Wayne County and flows E into Nahunta Swamp. |
| Slow Creek | rises in E Cherokee County and flows SW into Peachtree Creek. |
| Sluder Branch | rises in NW Buncombe County on E slopes of Hanlon Mountain and flows NE and then SE into Newfound Creek. |
| Sluice Gap | on the Swain County, N.C.-Sevier County, Tenn., line between Mount Kephart and The Sawteeth. |
| Sly | community in W Ashe County. |