| Rough Creek | rises in E Haywood County and flows SE into Beaverdam Creek. |
| Rough Fork | W Haywood County in Great Smoky Mountains National Park, is formed by the junction of Bear Branch and Horse Creek near lat. 35°36'10" N., long. 83°09'43" W., and flows NE into Palmer Creek. |
| Rough Fork | rises in S Macon County and flows NE into Wayah Creek. |
| Rough Knob | on the Haywood-Madison county line. |
| Rough Knob | E Macon County between Burgoin Gap and Riley Knob. |
| Rough Mountain | W Haywood County in Great Smoky Mountains National Park between Low Gap Branch and Big Branch; center near lat. 35°44'27" N., long. 83°10' W. |
| Rough Ridge | E Avery County. |
| Rough Ridge | W Haywood County in Great Smoky Mountains National Park, a short spur extending SE from Mount Sterling Ridge between Andy Branch and Woody Branch; center near lat. 35°40'55" N., long. 83°07'10" W. |
| Rough Run | rises in W Jackson County and flows SE into West Fork Tuckasegee River. |
| Rough Run Falls | just above the mouth of Rough Run in W Jackson County. |