| Reelsboro | community in W Pamlico County. Named for the local Reel family. |
| Reems Branch | rises in S Madison County and flows SE into Ponder Branch. |
| Reems Creek | rises in NE Buncombe County near Snowball Mountain and flows W into French Broad River. Probably named for a pioneer settler named Reems who was killed by Indians near present Weaverville about 1785. The name also appears in local records as Rims, Reams, and Rheims Creek. See also Lane Pinnacle. |
| Reems Creek | See Weaverville. |
| Reems Creek Township | N central Buncombe County. |
| Reepsville | community in W central Lincoln County. |
| Reese | community in NW Watauga County on Little Beaverdam Creek. Est. before 1900. Alt. 3,320. |
| Reese Creek | rises in E Cumberland County and flows SW into Lords Creek. |
| Reeves | community in S Columbus County. |
| Refuge | community in W Robeson County served by post office, 1893-1903. |