| Nichols Branch | rises in SW Macon County and flows NE into Nantahala River. |
| Nicholson | community in central Alamance County served by post office, 1879-1903. |
| Nicholson Creek | rises in central Transylvania County and flows SE into French Broad River. |
| Nicholsons Creek | rises in N Hoke County and flows S into Rockfish Creek. |
| Nicholsons Mills | community in NE Iredell County served by post office, 1876-1905. |
| Nick Bottom | loamy section in E Swain County on Oconaluftee River near the mouth of Goose Creek. |
| Nick Branch | rises in NE Cherokee County and flows N into Radder Creek. |
| Nick Creek | rises in S Haywood County and flows SE into West Fork Pigeon River. |
| Nick Gap | central Haywood County on the head of Messer Branch. |
| Nickajack Creek | rises in E Macon County and flows NE into Cullasaja River. |