| Little Spivey Creek | rises in N Yancey County and flows W into Tennessee, where it enters Spivey Creek. |
| Little Spruce Ridge | W Haywood County in Great Smoky Mountains National Park, a spur extending NE from Cataloochee Divide; center near lat. 35°33'35" N., long. 83°08'04" W., between Little Bald Branch and Bearpen Branch. |
| Little Steeltrap Creek | rises in N Swain County and flows SW into Forney Creek. |
| Little Stone Mountain | N Wilkes County on the W side of East Prong Roaring River. |
| Little Stonehouse Creek | rises in E Warren County and flows NE into Lake Gaston. |
| Little Sugar Creek | rises in central Mecklenburg County and flows SW into South Carolina, where it enters Sugar Creek. Appears as Shugan Creek on the Collet map, 1770, but with its present name on the Price map, 1808. |
| Little Sugar Loaf | community in central Bladen County served by post office, 1870-1901. |
| Little Swamp | rises in E Columbus County and flows SW into Juniper Creek. |
| Little Swamp | rises in S Nash County and flows SE into Toisnot Swamp. |
| Little Swamp Branch | rises in SW Johnston County and flows SE into Mill Swamp Branch. |