| Little Creek | rises in SW Nash County and flows SW into Moccasin Creek. |
| Little Creek | is formed in SE Orange County by the junction of Booker Creek and Bolin Creek; it flows E into SW Durham County, where it flows SE into New Hope Creek. |
| Little Creek | rises in W Stanly County and flows SW into Big Bear Creek. |
| Little Creek | rises in N Stokes County and flows SW into Peters Creek. |
| Little Creek | rises in W Surry County and flows SE into Snow Creek. |
| Little Creek | rises in E Wake County and flows SE into N Johnston County, where it enters Moccasin Creek. |
| Little Creek | rises in N Yancey County and flows SE into Cane River. |
| Little Creek | community on Little Creek S of Sams Gap, NE Madison County. Alt. 2,892. |
| Little Creek Gap | on the Haywood-Madison county line. |
| Little Creek Point | S Onslow County in New River. |